Molecular pathology of solid tumours: some practical suggestions for translating research into clinical practice.

Molecular pathology of solid tumours: translating research into clinical practice. Introduction and overview.

Research in pathology has increasingly come to involve molecular techniques, so that these are currently routine in academic histopathology and genetics laboratories. Molecular markers—largely from tumours, but also from the germline—have great potential for diagnosis, for directing treatment, and as indicators of outcome. However, in general, clinical practice has lagged behind research in mol...

Translating research findings to clinical nursing practice

AIMS AND OBJECTIVES To describe the importance of, and methods for, successfully conducting and translating research into clinical practice. BACKGROUND There is universal acknowledgement that the clinical care provided to individuals should be informed on the best available evidence. Knowledge and evidence derived from robust scholarly methods should drive our clinical practice, decisions and...

Radiotherapy techniques for intracranial tumours

ABSTRACTIntracranial tumours often require radiotherapeutic approaches that differ from other sites. Their specific requirements merit a specialized discussion. A brief review of radiotherapy techniques to treat intracranial tumours is presented with emphasis on the author’s own experience and work, where appropriate. A clinical introduction is presented first followed by a description of bot...

Quantitative Dengue Test: Is it Practical for Clinical Practice?

Beware of Bone Marrow: Incidental Detection and Primary Diagnosis of Solid Tumours in Bone Marrow Aspiration and Biopsies; A Study of 22 Cases

Background & objective: Introduction: First detection of any solid tumour as metastatic deposits in bone marrow directs clinicians to start searching for the primary tumour. Detection of bone marrow metastasis determines the stage of the malignancy, prognosis, mode of treatment, chemotherapeutic response and follow-up in case of relapse. The aim of the current...